Introduction:

Personality disorders correspond to a specific axis in the multiaxial mental diagnosis of a person, they represent distorted patterns in thinking and behavior, these disorders have a wide comorbidity with other mental disorders and diseases. Drugs are agents that modify the function of the organs which they interact with, the brain is one of them.

Objectives:

Establish the relationship between personality disorders and drug abuse on the intern patients in acute rooms of the Santa Rosita Psychiatric Hospital, Honduras.

Materials and Methods:

Descriptive, retrospective study, realised after having a random selection of the medical expedients of patients that entered because of drug abuse, with a significant sample from the patients medical records that had been also diagnosed with personality disorders by the Psychiatry service following the International Classification of Diseases (ICD-10) criteria while being in the hospital wards, this process followed by an application of a specific instrument to recollect detailed information and analysis using Epi Info 7 statistics program, looking to respond to the frequency of PD that coexists in patients with drug abuse.

Results:

The patients attended by cause of an determined licit or ilicit drug abuse presented personality disorders in 41% of the population, in the case of abuse of more than one drug when admitted to the hospital it ascended to 49% following de International Classification of Diseases.

Conclusions:

The most frequent personality disorders associated to the abuse of one drug, in descending order were: asocial borderline and mixed personality disorders. Nevertheless in case of several drug abuse at the time of their medical admission were Histrionic, Schizoid, Paranoid and other specific personality disorders.