<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1012-2966</journal-id>
<journal-title><![CDATA[Gaceta Médica Boliviana]]></journal-title>
<abbrev-journal-title><![CDATA[Gac Med Bol]]></abbrev-journal-title>
<issn>1012-2966</issn>
<publisher>
<publisher-name><![CDATA[Facultad de Medicina de la Universidad Mayor de San Simón]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1012-29662023000100099</article-id>
<article-id pub-id-type="doi">10.47993/gmb.v46i1.640</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Protocolo de manejo metabólico multidisciplinario de la litiasis urinaria]]></article-title>
<article-title xml:lang="en"><![CDATA[Multidisciplinary metabolic management protocol of urinary lithiasis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[VargasRocha]]></surname>
<given-names><![CDATA[Vladimir E.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Uzares Enriquez]]></surname>
<given-names><![CDATA[Daniela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Inturias Alvarado]]></surname>
<given-names><![CDATA[Wilder]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Caja Nacional de Salud Hospital Obrero N°2 ]]></institution>
<addr-line><![CDATA[Cochabamba ]]></addr-line>
<country>Bolivia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Caja Nacional de Salud Hospital Obrero N°2 Urología]]></institution>
<addr-line><![CDATA[Cochabamba ]]></addr-line>
<country>Bolivia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Caja Nacional de Salud Hospital Obrero N°2 ]]></institution>
<addr-line><![CDATA[Cochabamba ]]></addr-line>
<country>Bolivia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2023</year>
</pub-date>
<volume>46</volume>
<numero>1</numero>
<fpage>99</fpage>
<lpage>107</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_arttext&amp;pid=S1012-29662023000100099&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_abstract&amp;pid=S1012-29662023000100099&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_pdf&amp;pid=S1012-29662023000100099&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La enfermedad de cálculos renales, (nefrolitiasis) es un problema común en la atención en salud. Entre algunos de los factores que ayudan a la prevalencia de litiasis se encuentra la obesidad, altas temperaturas ambientales, y los climas secos. La frecuencia de las diferentes composiciones de los cálculos es: Oxalato de calcio entre el 70-80 %, fosfato calcico el 15 % (la apatita es más común y la brushita es menos común), Ácido úrico el 8%, cistina entre el 1-2 %, Estruvita -1%, Varios - &lt;1 %3.No existen muchos datos sobre la recurrencia de los mismos, pero se sabe que la tasa de recurrencia de litiasis urinaria es del 10 al 30% a los 5 años en pacientes que tienen cálculos de oxalato de calcio idiopáticos. Se plantea elaborar un protocolo de manejo metabólico multidisciplinario de la litiasis urinaria en base a la bibliografía actual tomando en cuanto los puntos de vistas de las especialidades destinadas al manejo del paciente con litiasis urinaria. Nuestro objetivo es establecer un protocolo de manejo capaz de identificar y establecer una terapia que pueda prevenir los cálculos urinarios de forma eficiente y económica, mejorando el pronóstico y minimizando las complicaciones.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Kidney stone disease is a common problem in health care. Among the factors that contribute to the prevalence of lithiasis are obesity, high environmental temperatures, and dry climates. The frequency of the different stone compositions is: Calcium Oxalate 70-80%, Calcium Phosphate -15% (Apatite is more common and Brushite is less common), Uric Acid 8%, Cystine - 1-2%, Struvite -1%, Various - &lt;1%3. There are not many data on their recurrence, but it is known that the recurrence rate of urinary lithiasis is 10 to 30% at 5 years in patients with idiopathic calcium oxalate stones. It is proposed to develop a multidisciplinary metabolic management protocol for urinary lithiasis based on the current bibliography, taking the point of specialties dedicated to the management of patients with urinary lithiasis. Our goal is to establish a management protocol capable of identifying and establishing a therapy that can efficiently and economically prevent urinary stones, improving prognosis and minimizing complications.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[nefrolitiasis]]></kwd>
<kwd lng="es"><![CDATA[litiasis urinaria]]></kwd>
<kwd lng="es"><![CDATA[oxalatos]]></kwd>
<kwd lng="es"><![CDATA[protocolos clínicos]]></kwd>
<kwd lng="en"><![CDATA[nephrolithiasis]]></kwd>
<kwd lng="en"><![CDATA[urolithiasis]]></kwd>
<kwd lng="en"><![CDATA[oxalates]]></kwd>
<kwd lng="en"><![CDATA[clinical protocols]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<label>1</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Scales]]></surname>
<given-names><![CDATA[CD Jr]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Prevalence of kidney stones in the United States]]></article-title>
<source><![CDATA[Eur Urol]]></source>
<year>2012</year>
</nlm-citation>
</ref>
<ref id="B2">
<label>2</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Chewcharat A]]></surname>
<given-names><![CDATA[CG]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Trends in the prevalence of kidney stones in the United States from 2007 to 2016]]></article-title>
<source><![CDATA[Urolithiasis]]></source>
<year>2021</year>
<volume>49</volume>
<numero>1</numero>
<issue>1</issue>
</nlm-citation>
</ref>
<ref id="B3">
<label>3</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Lieske]]></surname>
<given-names><![CDATA[JC]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Stone composition as a function of age and sex]]></article-title>
<source><![CDATA[Clin J Am Soc Nephrol]]></source>
<year>2014</year>
<volume>9</volume>
<numero>12</numero>
<issue>12</issue>
</nlm-citation>
</ref>
<ref id="B4">
<label>4</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Gary]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Curhan]]></surname>
<given-names><![CDATA[MS]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Kidney stones in adults: Epidemiology and risk factors]]></article-title>
<source><![CDATA[Uptodate]]></source>
<year>2021</year>
</nlm-citation>
</ref>
<ref id="B5">
<label>5</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Curhan GC]]></surname>
<given-names><![CDATA[TE]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[24-h uric acid excretion and the risk of kidney stones]]></article-title>
<source><![CDATA[Kidney Int]]></source>
<year>2008</year>
<volume>73</volume>
<numero>4</numero>
<issue>4</issue>
</nlm-citation>
</ref>
<ref id="B6">
<label>6</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Sorensen MD]]></surname>
<given-names><![CDATA[EBSKKALLSNSM]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Impact of calcium intake and intestinal calcium absorption on kidney stones in older women the study of osteoporotic fractures]]></article-title>
<source><![CDATA[Journal Urology]]></source>
<year>2012</year>
<volume>187</volume>
<numero>4</numero>
<issue>4</issue>
</nlm-citation>
</ref>
<ref id="B7">
<label>7</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Bayomy]]></surname>
<given-names><![CDATA[O]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Disentangling the Relationships Between the Renin-Angiotensin-Aldosterone System, Calcium Physiology, and Risk for Kidney Stones]]></article-title>
<source><![CDATA[J Clin Endocrinol Metab]]></source>
<year>2020</year>
<volume>105</volume>
<numero>6</numero>
<issue>6</issue>
</nlm-citation>
</ref>
<ref id="B8">
<label>8</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Li]]></surname>
<given-names><![CDATA[X]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Outcomes of long-term follow-up of asymptomatic renal stones and prediction of stone-related events]]></article-title>
<source><![CDATA[BJU]]></source>
<year>2019</year>
<volume>123</volume>
<numero>3</numero>
<issue>3</issue>
</nlm-citation>
</ref>
<ref id="B9">
<label>9</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Kobayashi]]></surname>
<given-names><![CDATA[T]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Impact of date of onset on the absence of hematuria in patients with acute renal colic]]></article-title>
<source><![CDATA[J Urology]]></source>
<year>2003</year>
<volume>170</volume>
<numero>4</numero>
<issue>4</issue>
</nlm-citation>
</ref>
<ref id="B10">
<label>10</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Qaseem]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Dietary and pharmacologic management to prevent recurrent nephrolithiasis in adults: a clinical practice guideline from the American College of Physicians]]></article-title>
<source><![CDATA[Ann Intern Med]]></source>
<year>2014</year>
<volume>161</volume>
<numero>9</numero>
<issue>9</issue>
<page-range>659</page-range></nlm-citation>
</ref>
<ref id="B11">
<label>11</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[MC]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[First Drug Approved for Rare Genetic Disorder Affecting Kidneys]]></article-title>
<source><![CDATA[JAMA]]></source>
<year>2021</year>
<volume>19</volume>
<numero>325</numero>
<issue>325</issue>
</nlm-citation>
</ref>
</ref-list>
</back>
</article>
