<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1726-8958</journal-id>
<journal-title><![CDATA[Revista Médica La Paz]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Méd. La Paz]]></abbrev-journal-title>
<issn>1726-8958</issn>
<publisher>
<publisher-name><![CDATA[Colegio Médico de La Paz]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1726-89582025000100077</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[DISFUNCIÓN PLACENTARIA SEVERA ASOCIADA A RCIU TEMPRANO. REPORTE DE CASO]]></article-title>
<article-title xml:lang="en"><![CDATA[SEVERE PLACENTARY DYSFUNCTION ASSOCIATED WITH EARLY IUGR. CASE REPORT]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ledezma Cuba]]></surname>
<given-names><![CDATA[Laydi Dayanna]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[del Villar Villarroel]]></surname>
<given-names><![CDATA[Max Fernando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Soria Galvarro]]></surname>
<given-names><![CDATA[Nicole Trino]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gomez Webber]]></surname>
<given-names><![CDATA[Micaela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Caja Nacional de Salud Hospital Materno Infantil Servicio de Obstetricia]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="Af2">
<institution><![CDATA[,Caja Nacional de Salud Hospital Materno Infantil Servicio de Obstetricia]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="Af3">
<institution><![CDATA[,Caja Nacional de Salud Hospital Materno Infantil Obstetricia]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="Af4">
<institution><![CDATA[,Caja Nacional de Salud Hospital Materno Infantil Servicio de Ginecología - Obstetricia]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<volume>31</volume>
<numero>1</numero>
<fpage>77</fpage>
<lpage>82</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_arttext&amp;pid=S1726-89582025000100077&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_abstract&amp;pid=S1726-89582025000100077&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_pdf&amp;pid=S1726-89582025000100077&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN La restricción del crecimiento intrauterino se define como aquel feto que no alcanza su potencial de crecimiento teniendo una talla y peso menor al correspondiente para la edad gestacional. Si es temprana, antes de las 32 semanas, se atribuye por lo general al compromiso placentario que restringe el suministro necesario para el desarrollo fetal. Por otro lado, la insuficiencia placentaria es un síndrome anatomo-clínico desarrollado por causas extrínsecas relacionadas con la madre (diabetes, toxemias, estados carenciales) o intrínsecas, relacionadas con la senescencia placentaria. Se presenta el caso de una paciente de 38 años de edad con mala historia obstétrica que se interna a las 20 semanas de embarazo por presentar oligohidramnios severo. En el abordaje de la etiologia, se realizan exámenes de rutina, inmunología y valoración por genética descartando causas infecciosas, autoinmunes y fetales. Llama la atención el Doppler de arterias uterinas alterado con IP medio de 1.6 que indica mayor resistencia vascular uterina y una disminución de la perfusión a través de la placenta lo que puede llevar al desarrollo de restricción de crecimiento intrauterino y preeclampsia.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Intrauterine growth restriction is defined as a fetus that does not reach its growth potential, having a size and weight less than the corresponding one for the gestational age. If it is early, before 32 weeks, it is usually attributed to placental obstructive involvement that restricts the supply necessary for fetal development. On the other hand, placental insufficiency is an anatomical-clinical syndrome developed by extrinsic causes related to the mother (diabetes, toxemia, deficiency states) or intrinsic causes, related to placental senescence. The case of a 38-year-old patient with a poor obstetric history who was admitted at 20 weeks of pregnancy due to severe oligohydramnios is presented. In search of the cause, routine examinations, immunology and genetic evaluation are performed, ruling out infectious, autoimmune and fetal causes. Of note is the altered Doppler of uterine arteries with a mean IP of 1.6, which indicates greater uterine vascular resistance and a decrease in perfusion through the placenta, which can lead to the development of intrauterine growth restriction and preeclampsia.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Insuficiencia placentaria]]></kwd>
<kwd lng="es"><![CDATA[RCIU]]></kwd>
<kwd lng="es"><![CDATA[DOPPLER]]></kwd>
<kwd lng="en"><![CDATA[Placental Insufficiency]]></kwd>
<kwd lng="en"><![CDATA[IUGR]]></kwd>
<kwd lng="en"><![CDATA[DOPPLER]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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