<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2077-3323</journal-id>
<journal-title><![CDATA[Revista Ciencia y Cultura]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cien Cult]]></abbrev-journal-title>
<issn>2077-3323</issn>
<publisher>
<publisher-name><![CDATA[Universidad Católica Boliviana]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2077-33232023000200091</article-id>
<article-id pub-id-type="doi">10.35319/rcyc.2023511207</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[La fragilidad osmótica y su relación con la anemia espacial]]></article-title>
<article-title xml:lang="en"><![CDATA[Osmotic Fragility and its Relationship with Space Anemia]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Agramont]]></surname>
<given-names><![CDATA[Natalia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Carrasco]]></surname>
<given-names><![CDATA[Marcia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Flores]]></surname>
<given-names><![CDATA[Belén]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Quenta]]></surname>
<given-names><![CDATA[Daira]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chávez]]></surname>
<given-names><![CDATA[Georgina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Católica Boliviana &#8220;San Pablo&#8221; Ingeniería Bioquímica y de Bioprocesos ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Bolivia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Católica Boliviana &#8220;San Pablo&#8221; Ingeniería Bioquímica y de Bioprocesos ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Bolivia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Católica Boliviana &#8220;San Pablo&#8221; Ingeniería Bioquímica y de Bioprocesos ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Bolivia</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidad Católica Boliviana &#8220;San Pablo&#8221; Ingeniería Bioquímica y de Bioprocesos ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Bolivia</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Universidad Católica Boliviana &#8220;San Pablo&#8221; Centro de Investigación en Agua, Energía y Sostenibilidad Ingeniería Biomédica]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Bolivia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2023</year>
</pub-date>
<volume>27</volume>
<numero>51</numero>
<fpage>91</fpage>
<lpage>106</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_arttext&amp;pid=S2077-33232023000200091&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_abstract&amp;pid=S2077-33232023000200091&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.bo/scielo.php?script=sci_pdf&amp;pid=S2077-33232023000200091&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El presente artículo presenta el procedimiento para realizar la fragilidad osmótica, una prueba realizada para observar el comportamiento de los eritrocitos en diferentes concentraciones de NaCl (medios hipotónicos). Esta prueba es realizada en personas con anemia y permite identificar la fragilidad de los eritrocitos. También puede ser realizada en astronautas, los cuales sufren anemia espacial producida por el cambio de las condiciones en el espacio. Sin embargo, el origen de esta enfermedad aún no ha sido identificado, por lo que se plantea que es producida por la hipergravedad a la que los astronautas son expuestos en el momento del despegue.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract The following article shows the procedure needed to make a fragility osmotic curve, which is a test made to identify the behavior of erythrocytes at different concentrations of NaCl (hypotonic solution). This test is realized with anemic people, and it lets us identify the fragility of the erythrocytes. It can also be applied in astronauts who also suffer from space anemia produced by the different conditions of the new environment that they are exposed to. Nevertheless, the causes of this illness have not been identified, hence the team suggests this is caused by hypergravity which astronauts are exposed to in the moment they are launched to space.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Fragilidad osmótica]]></kwd>
<kwd lng="es"><![CDATA[hipergravedad]]></kwd>
<kwd lng="es"><![CDATA[anemia espacial]]></kwd>
<kwd lng="es"><![CDATA[glóbulos rojos]]></kwd>
<kwd lng="en"><![CDATA[Osmostic fragility]]></kwd>
<kwd lng="en"><![CDATA[hypergravity]]></kwd>
<kwd lng="en"><![CDATA[spatial anaemia]]></kwd>
<kwd lng="en"><![CDATA[red blood cells]]></kwd>
</kwd-group>
</article-meta>
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