Resumo

TANDAZO PERALTA, Gabriela Elizabeth  e  BRAVO CRESPO, David Israel. In vitro antifungal activity of laurel extract “Laurus nobilis” against Candida albicans. Vive Rev. Salud [online]. 2025, vol.8, n.23, pp.392-405.  Epub 01-Maio-2025. ISSN 2664-3243.  https://doi.org/10.33996/revistavive.v8i23.385.

Infections caused by Candida albicans have a recurrent incidence globally, due to the use of antifungals, therefore, many investigations have sought feasible alternatives based on medicinal plants. Objective To evaluate the in vitro antifungal effect of laurel extract "Laurus nobilis" against Candida albicans. Materials and methods An experimental, quantitative study was carried out, whose classification belongs to a pure experiment, with a non-probabilistic sampling by convenience, from a study population comprised of commercial strains of Candida albicans ATCC 10231 and the extract of Laurus nobilis. The inhibition of the growth of strain ATCC 10231 in dilutions of 100%, 75%, 50% 25% and 10% of Laurus nobilis extract with dimethyl sulfoxide (DMSO) was evaluated. The results revealed that Laurus nobilis extract at concentrations of 100, 75 and 50% presented an antifungal action against Candida albicans. This fact is due to the presence of inhibition halos, which according to the Duraffourd scale, are classified as sensitive. It is concluded that the results obtained from the inhibition halos in the different concentrations of the laurel extract, in which it can be affirmed that it does have an antifungal effect against Candida albicans.

Palavras-chave : Antifungal activity; Candida albicans; Alcoholic extract; Inhibition halos; Medicinal plants; Bioactive principles.

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