Abstract

CASTILLO, Marcia Gabriela  and  CHALMA, Pedro Rosendo. Relationship of thyroid alterations with lipid factors in young adults. Vive Rev. Salud [online]. 2025, vol.8, n.22, pp.342-356.  Epub Jan 22, 2025. ISSN 2664-3243.  https://doi.org/10.33996/revistavive.v8i22.380.

It is known that thyroid hormones regulate lipid metabolism and that thyroid disorders are common in dyslipidemic patients. On the other hand, dyslipidemia is not only a risk factor for cardiovascular disease (CVD) and nonalcoholic fatty liver disease (NAFLD), but can also lead to insulin resistance and oxidative stress. The aim of this review was to determine the different thyroid alterations in relation to the lipid profile in a young adult population. For this purpose, a review was made of the information available in databases such as Scopus, Pubmed, Elsevier, among others, in accordance with the recommendations of the PRISMA statement. Articles published in Spanish and English that reported thyroid alterations related to lipid factors in young adults were included. The literature review found that serum levels of total cholesterol (TC), total triglycerides (TG) and very low density cholesterol (VLDL) were significantly elevated and were proportionally related to serum thyroid stimulating hormone (TSH) concentration and inversely related to high density lipoprotein (HDL-C). The analysis of the literature reviewed confirms the high prevalence of thyroid dysfunction (TD) worldwide, with a significant frequency of subclinical hypothyroidism and euthyroidism in various populations. The importance of timely diagnosis and treatment of these disorders lies in their close relationship with cardiovascular diseases, dyslipidemias and other metabolic risk factors.

Keywords : Thyroid; Lipid profile; Clinical hypothyroidisms; Euthyroidism.

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