Abstract

CASTILLO, Karen Elena Bermeo; HERMIDA, Danilo Fernando Rea  and  BERMEO, Karen Michelle Tenezaca. Complications of Parkinson’s Disease related to SARS-CoV-2 infection. Vive Rev. Salud [online]. 2023, vol.6, n.17, pp.663-676.  Epub May 08, 2023. ISSN 2664-3243.  https://doi.org/10.33996/revistavive.v6i17.254.

SARS-CoV-2 was recorded in Wuhan City-China for the first time in December 2019. The impact of this new pathology in patients with Parkinson's Disease was negative, in that it uncovered the development of severe complications following this infection, in addition, the virus may indirectly affect the central nervous system through inflammatory response and cytokine release, which may have a negative impact on neuronal function, leading to further impairment in the quality of life of these patients. Objective. To describe the complications of Parkinson's disease related to SARS-CoV-2 infection. Methodology. A systematic review was carried out through a database search. We included studies published between 2019 and 2022 that met inclusion and exclusion criteria and reported on complications in patients with Parkinson's disease. Results. We proceeded to read the full text of each article, being excluded 13 articles, because they did not fully meet inclusion criteria, presented another subject or had an unclear methodology, 17 as a result. Conclusion. It is important to recognize that COVID-19 is a multifaceted disease that primarily affects the respiratory system, but can also have impacts on other body systems, including the nervous system. While it has been observed that some Parkinson's patients experience worsening of motor and non-motor symptoms during COVID-19 infection, among the symptoms with the highest prevalence of complications were sleep disturbances, mood disturbances, bradykinesia, rigidity, tremor, gait disturbances.

Keywords : SARS-CoV-2; Parkinson Disease; COVID-19.

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