Resumo

GONZALES, Anibal Oblitas; ORTIZ, José Uberli, Herrera  e  FIESTAS, Richard Williams Hernández. Monkeypox, insights into what is known. Vive Rev. Salud [online]. 2023, vol.6, n.17, pp.560-579.  Epub 08-Maio-2023. ISSN 2664-3243.  https://doi.org/10.33996/revistavive.v6i17.246.

Smallpox is a zoonotic disease endemic to West and Central Africa, but the current outbreak is showing an unusual spread throughout the world despite its limited ability to transmit from human to human, a situation that has raised global health concern. Objective. To identify monkeypox, description of monkeypox virus, current outbreak of monkeypox, etiology, transmission, signs and symptoms, diagnosis, vaccination and antiviral treatment. Methodology. A systematic review was carried out in PubMed, Ovid and LILACS, using Boolean operators such as, "monkeypox" OR "MPXV" OR "human monkeypox" OR "monkeypox virus", a total of 986 records were identified, in English and Spanish. The screening phase collected 59 records between scientific articles and grey literature published between 2010 and 2022. The review process was developed under the standards of the PRISMA method; eligibility included assessment of scientific quality by checklists, and inclusion contemplated the criteria of quality of evidence and grading of the strength of recommendation. Results. A total of 287 records were found in PubMed, 699 in Ovid Medline®, and 986 electronic records were located. Conclusion. The increase in human-to-human transmission endangers the family environment and health care providers. Skin rashes are the pathognomonic sign during clinical assessment. The herd immunity achieved during human smallpox vaccination has been reduced, contributing to the increase in cases and spread.

Palavras-chave : Monkeypox; Disease Outbreak; Public Health.

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