Resumo

AREVALO ORDONEZ, Tamara. Standarization of the Internacional Normalized Index in pre-surgical patients at Hospital San Juan de Dios of Cuenca. Vive Rev. Salud [online]. 2022, vol.5, n.13, pp.179-190.  Epub 23-Abr-2022. ISSN 2664-3243.  https://doi.org/10.33996/revistavive.v5i13.140.

The International Normalized Ratio (INR) is a type of mathematical calculation based on prothrombin time testing. The safety and efficacy of therapy depend on the anticoagulant effect they receive within the therapeutic range set by the physician based on the study of their clotting times, specifically expressed as the INR range. To establish the reference ranges of the INR applied in results obtained in male and female patients between 18 and 60 years of age at the San Juan de Dios Hospital in Cuenca, during the months of January to June 2021. The data were collected from 699 patients who attended the outpatient clinic of the Hospital San Juan de Dios de Cuenca in the hematology area, including thromboplastin time values and their INR referent based on the ISI established in the reagent issued by the manufacturer. Normal INR values were established, which vary according to the patient's sex. For the male sex values with a lower limit of 0.82 and an upper limit of 1.16; for the female sex with a lower limit of 0.51 and an upper limit of 1.51. The INR values vary according to sex, with the values for men being higher in relation to those for women in the lower range. Evidently, the influencing factors are related to sex, age, diet and above all the patient's genetics.

Palavras-chave : INR; ISI; Coagulation; Prothrombin time.

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