Introduction:

Antimicrobial resistance raises a serious threat to health worldwide. Infections by "ESKAPE" bacteria represent major resistance problems, since they can present more than one resistance mechanism and also have the ability to transmit other bacteria. In Bolivia, unfortunately, there are no Bolivian authors who have published articles explaining the multi-resistance of "ESKAPE" Bacteria in third level hospitals.

Objective:

To describe the antimicrobial sensitivity and resistance profile of “ESKAPE” bacteria isolated in all inpatient units of Hospital Del Norte in 2019.

Material and methods:

Observational, descriptive study, included 836 isolates obtained from January to December 2019 from patients hospitalized in all units of Hospital del Norte. WHONET software was used and the variables studied were: age, gender, type of sample, hospitalization room and resistance profile of each of the microorganisms under study.

Results:

The antimicrobial sensitivity and resistance profile of each "ESKAPE" bacteria was elaborated and described, and it was found that Enterobacteriaceae have a higher frequency, with Escherichia coli is being the most prevalent pathogen; it was determined that there is a higher frequency in adult patients, with a higher prevalence in the female gender. The frequency by type of sample shows that the first three places are occupied by urine, lower respiratory tract and abscess samples. Intensive care, internal medicine, and surgery services are the most critical areas. The percentages of resistance were obtained for each of the microorganisms studied according to the hospitalization room. ESBL and MRSA are the main phenotypic resistance mechanism found in the hospital.

Conclusions:

The results obtained show that the epidemiological map of antimicrobial resistance at Hospital del Norte presents higher percentages in relation to similar epidemiological maps of other hospitals in Latin America.

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