Resumen

CARMINA GARCIA, CLAUDIA HEREDIA. Estrés crónico: ejemplo de interacción entre sistemas nervioso, inmuno y endocrino: Chronic stress: example of interaction between nervous, immune and endocrine systems. Rev.Cs.Farm. y Bioq [online]. 2018, vol.6, n.2, pp.97-110. ISSN 2310-0265.

Abstract Stress is the body's response to external conditions that disturb the person's emotional balance and produce biochemical changes in the body. Currently, it has become a problem that affects all human beings, without distinction of race, gender or socioeconomic status. The physiological response to stress allows the human being to adapt to or cope with this unfavorable situation. The response to stress is controlled by the systems: nervous (SN), endocrine (SE) and immune (SI), which is currently known as Psycho-neuro-immune-endocrine (PNIE) interaction. This has been demonstrated when a prolonged exposure to stress increases the concentrations of glucocorticoids and catecholamines which leads to the suppression of the functioning of the immune system, increasing the susceptibility to contract infections. Therefore, it is important to approach the sick patient in a holisticway, considering their emotions, beliefs and psycho-social factors, as well as the functional integration of the nervous, immune and endocrine systems since the balance of these maintains homeostasis. When we understand that systems are integrated and that one affects the other, we become more aware that by controlling our impulses, motivating ourselves, avoiding that anguish, discouragement, fear or sadness inter-fere with our emotions, we take control of our emotions and we channel that the communi-cation molecules between the cells of the SN, SI and SE, maintain the state of equilibrium that preserves our life.

Palabras clave : Stress; PNIE Network; Psycho-social.

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