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Revista de Investigacion e Informacion en Salud
versão impressa ISSN 2075-6194versão On-line ISSN 2075-7208
Resumo
DAVILA-COLQUE, Isabel Paola. Evaluation of the Analytical Performance of Transaminases and Alkaline Phosphatase, in automated equipment versus semi-automated equipment. Rev. Inv. Inf. Sal. [online]. 2025, vol.20, n.48, pp.16-24. Epub 30-Jun-2025. ISSN 2075-6194. https://doi.org/10.52428/20756208.v20i48.1228.
Introduction:
In the clinical laboratory, it is important to evaluate a method before being used, even more so when a team is implemented or when it is desired to compare between others that perform the same measurement, this evaluation allows to design and implement an adequate internal quality control (ICC), in addition to comparing the performance and stability of the measurement system, to guarantee the reliability of the results. The objective of the present work is to evaluate the analytical performance of transaminases and alkaline phosphatase in an automated equipment, compared to a semi-automated equipment.
Material and Methods:
Observational, prospective, longitudinal study at the application level, where the EP15-A2 protocol was used to verify precision and accuracy, using commercial control material, subsequently the sigma metric was calculated for six months, to evaluate the performance of the method.
Results:
When verifying precision and accuracy in transaminases and alkaline phosphatase, the values were accepted according to the EP15A2 protocol. The sigma metric obtained was greater than 4, indicating good performance in both teams.
Discussion:
It is concluded that both teams met the precision and accuracy verification requirements, and the verification was accepted. According to the sigma metric, it is concluded that the automated team performs better than the semi-automated team.
Palavras-chave : Analytical quality control; clinical trial protocol; evaluation study; laboratory equipment; total quality management.












