Abstract

BALVANERA RODARTE, Erika Alexander; VALLE LEAL, Jaime Guadalupe; DIAZ CORRAL, Karla Fabiola  and  DUARTE BURBOA, Marcela Alejandra. AGRANULOCYTOSIS SECONDARY TO VANCOMYCIN USE IN PEDIATRICS. CASE REPORT. Rev Cient Cienc Méd [online]. 2023, vol.26, n.1, pp.99-103.  Epub June 31, 2023. ISSN 1817-7433.

Vancomycin is a commonly used antibiotic in hospitalized patients. Multiple adverse effects related to this drug have been described, of which agranulocytosis is a rare but potentially serious entity. This case shows a medical consequence secondary to the prolonged use of this antibiotic, generating profound neutropenia after 24 days of treatment, presenting clinically with an isolated feverish peak. It is assumed that this situation is the consequence of an inadequate immunological response of the host, for which reason the suspension of the etiological agent is the key to treatment. There are few reports of these effects in the pediatric population and should be considered a side effect that requires close monitoring to avoid clinical repercussions.

Keywords : Vancomycin; agranulocytosis; neutropenia; antibiotic.

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