Abstract

NAVARRO TURCIOS, Steven Josue; SANTAMARIA VASQUEZ, Mario José  and  MARADIAGA MONTOYA, Ramon Yefrin. POLYGLANDULAR AUTOIMMUNE SYNDROME TYPE III-C ASSOCIATED WITH VITILIGO; CASE REPORT IN HONDURAS. Rev Cient Cienc Méd [online]. 2023, vol.26, n.1, pp.81-87.  Epub June 31, 2023. ISSN 1817-7433.

Polyglandular autoimmune syndromes (PAS) are a series of functional anomalies that can cause immunitary deregulation affecting multiple endocrine glands. Chronic pathologies in adult patients are not always independent from one another, but rather, are unique defects with multiple clinical presentations.We report an elderly female patient with a history of vitiligo, alopecia, hypertension and type 2 diabetes mellitus who came into a consultation for asthenia, adynamia and drowsiness for approximately 10 months. The physical exam showed a pyknic biotype, myxedema, dry skin and goiter.Test results show TSH (12 lU/ml), free T4 (0. 2 ng/dl), Anti TPO 168.70 lU/ml, USG reported thyroid goiter and a micro nodular pattern where the diagnosis of Hashimoto's thyroiditis is made. This study demonstrated that, through understanding the pathological history alongside the current disease, we can diagnose a polyglandular autoimmune syndrome type III-C.

Keywords : Polyendocrinopathies autoimmune; vitíligo; Hashimoto disease.

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