Resumo

QUINTANILLA FERRUFINO, Gustavo Jared et al. CARDIOVASCULAR DISORDERS CAUSED BY CLINICAL AND SUBCLINICAL HYPOTHYROIDISM. Rev Cient Cienc Méd [online]. 2020, vol.23, n.1, pp.52-60. ISSN 2077-3323.

Hypothyroidism is an endocrine disorder in which the thyroid gland has a diminished function; having as a consequence the loss of homeostasis of the body, therefore, altering its proper functioning. To diagnose this disease, physical examination, blood tests and thyroid stimulating hormone tests are utilized. Since the cardiovascular system and the thyroid gland are physiological related, the general disorders of the thyroid gland greatly affect the cardiovascular system. The intracellular and extracellular mechanisms of thyroid hormones are detailed; and, using this information, all the morphological and physiological changes that this pathology causes in the heart and on smooth muscle cells are explained. In addition, the implications of the disease on the myocardium, on hemodynamics, its relation to congestive heart failure, hypertension and general effects on blood vessels are revealed, with the objective of describing the relationship between clinical and subclinical thyroid hypofunction as a determining risk factor for the development of cardiovascular disorders.

Palavras-chave : hypothyroidism; triiodothyronine; thyroxine; heart defects; cardiovascular diseases.

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