Abstract

BETRAN, Ana et al. BACTERIEMIAS CAUSED BY STAPHYLOCOCCUS AUREUS: RISK FACTORS ASSOCIATED TO METHICILLIN RESISTANCE. Rev Cient Cienc Méd [online]. 2020, vol.23, n.1, pp.44-51. ISSN 2077-3323.

Introduction: The objective of this work has been to identify the risk factors that could favor the appearance of methicillin resistance in isolates of Staphylococcus aureus (SA) and those that would influence mortality due to bacteremia produced by this pathogen. Methods: An observational case-control study was carried out in 57 patients diagnosed with bacteremia by SA at the Barbastro's Hospital. Pearson Chi square statistical test, Fisher test and multiple logistic regression were used for the analysis. Results: Of the total Bacteriemias, 63.15% corresponded to methicillin-sensitive Staphylococcus aureus (MSSA) and 36.84% to methicillin-resistant Staphylococcus aureus (MRSA). Nosocomial acquisition of the infection, previous use of antibiotics and the age over 65 years, were associated with methicillin resistance. The mortality of cases of MRSA and SAMS bacteremia was 28.57% and 36.1 1% respectively, these differences being statistically not significant. All isolates were sensitive in vitro to vancomycin. Conclusions: In our health sector, the most effective strategies to reduce the incidence of MRSA bacteremia would be the control and proper use of antimicrobials and the application of nosocomial infection prevention programs. Patients with SA bacteremia, are not associated with more mortality caused by MRSA.

Keywords : Staphylococcus aureus; methicillin; bacteremia.

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