Abstract

ANAYA MUNOZ, Santiago Franklin; CALVO ORELLANA, Eldy Ericka; VALDEZ RAMALLO, María Alexandra  and  SANTA CRUZ RODRIGUEZ, Adriana C.. ANTIMICROBIAL ACTIVITY OF WIRA WIRA AND CERRAJA AGAINST STAPHYLOCOCCUS, ENTEROCOCCUS, PSEUDOMONAS AND ESCHERICHIA. Rev Cient Cienc Méd [online]. 2020, vol.23, n.1, pp.15-21. ISSN 2077-3323.

Introduction: The use of plants with various ethnomedicinal purposes is an ancestral practice and currently common in a vast part of the population of Bolivia. General objective: To identify if the extracts of both plants present in our environment have antimicrobial activity against pathogenic bacteria and to determine their toxicity through the bioassay of biological tests. Materials and Methods: Descriptive study; Universe, Wira Wira collected from Valle Alto in Cochabamba and Cerraja collected from Cercado; Sample, we obtained one kilogram of each, Wira Wira and Cerraja randomly; Methods, different techniques were used to extract the active ingredients, biological tests were performed to determine their toxicity and antimicrobial activity was determined by the agar diffusion method. Results: Wira Wira demonstrated antimicrobial activity with 4 extracts; stem alcoholic, flower and alcoholic depleted of leaves against E. faecalis and S. aureus, and aqueous of leaves against P. aeruginosa and S. aureus. On the other hand, there was no evidence of antibacterial activity with the cerraja extracts. Conclusions: Wira Wira is a candidate for further studies aimed at the identification of the pure active compound (s) with antibacterial activity, all this backed up by the positive results in the agar diffusion tests grown with pathogenic bacteria. Unlike the results that demonstrate the antibacterial activity of the Cerraja in research carried out in other parts of the world, it is not the case of the one in our territory, whose extracts did not present any antimicrobial activity, demonstrating the possibility and linking the variation in plant compounds with the ecosystems in which it develops.

Keywords : In Vitro Techniques; Anti-Bacterial Agents; Achyrocline; Sonchus.

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