Abstract

CUAURO RUIZ, Gabriela et al. FRECUENCY OF BARRET'S ESOPHAGUS FOR GASTROESOPHAGEAL REFLUX IN THE CENTRAL UNIVERSITY OF VENEZUELA. Rev Cient Cienc Méd [online]. 2018, vol.21, n.1, pp.21-25. ISSN 2077-3323.

Introduction: Reflux disease develops when gastric content causes esophageal and extra esophageal symptoms and/or complications. The esophageal complications include reflux, reflux esophagitis and Barrett's esophagus. The last is a pre-malignant condition characterized by a specialized intestinal metaphase whose importance lies in the knowledge of dysplasia due to its evolution to cancer. Previous investigations determined the prevalence of: dysplasia in Barrett's esophagus 33,3%; non erosive reflux disease 82,70% and erosive 17,30%; esophagitis with endoscopic and morphologic findings 84,37%. Objective: To evaluate the prevalence of Barrett's esophagus in patients with reflux and reflux esophagitis in the Anatomopathologic Institute of Universidad Central de Venezuela. Method: A descriptive and retrospective study was conducted. There were evaluated the esophageal endoscopic biopsies between 2005-2015, with diagnosis of reflux and reflux esophagitis.The presence or absence of dysplasia was reviewed in the Barrett's esophagus cases, with the respective grade. Absolute and relative frequencies were obtained by a descriptive analysis. Results: 35,85% of cases were reflux and 64,12% were reflux esophagitis, both with women predominance and the average age was 55,2 and 53,1 years respectively. Eighteen cases (8%) with Barrett's esophagus were related to reflux disease. Low grade dysplasia represented 5,55%, indefinite for dysplasia 50% and negative for dysplasia 44,44%. Conclusions: The prevalence of Barrett's esophagus associated with gastroesophageal reflux disease was 8%.The highest frequency was in the female sex with 66,66%, and the ages between 30 and 78 years with an average of 59,25 years.

Keywords : Biopsy; esophagus; reflux esophagitis; Barrett esophagus; cancer.

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