Abstract

GARCIA DE SALGUEIRO, Carmiña et al. Thyroid diseases in people with Down syndrome in the state of La Paz - Bolivia. Rev Cient Cienc Méd [online]. 2017, vol.20, n.1, pp.11-15. ISSN 1817-7433.

Down Syndrome is associated with several forms of dysthyroidism, hypothyroidism is the most common on this population. Alteration in thyroid function may increase the morbidity of this syndrome, decreasing the quality and life expectancy in these patients. The main objective of the present study was describe the state of thyroid function in patients with Down Syndrome of the Aywiña Foundation and the Down Bolivia Foundation in the department of La Paz, through the determination of biochemical tests of the thyroid axis. The target group were consisted of 30 individuals, for which 19 males and 11 females. The obtained results indicate a 50% of dysthyroidism, the population with the highest incidence of thyroid alteration were those are younger than 13 years. The main pathology was subclinical hypothyroidism (24%), followed by subclinical autoimmune hypothyroidism. It is noteworthy that a high percentage of hyperthyroidism (13%) was observed, which is higher than reported by other authors. Also there were no significant differences between genders. The high incidence of dysthyroidism found suggests that the population with Down Syndrome in the department of La Paz is vulnerable to this type of disorder, confirming what has been reported in other populations. Due to the presence of thyroid dysfunction increases the complications of this syndrome, it is important to perform annual tests that evaluate thyroid function and the need to have reference ranges for the biochemical tests of the thyroid axis in the population with Down Syndrome of our country.

Keywords : Down Syndrome; Thyroid Diseases; hypothyroidism.

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