Abstract

ROMERO LEDEZMA, Karla Pamela  and  MARTINEZ ARA, Mauricio Ara. METAMIZOL EFFICACY AND SAFETY - METAMIZOL TRAMADOL IN COMPARISON -KETOROLAC FOR POSTOPERATIVE PAIN MANAGEMENT IN LAPAROSCOPIC CHOLECYSTECTOMY. Rev Cient Cienc Méd [online]. 2016, vol.19, n.1, pp.39-44. ISSN 2077-3323.

The International Association for the Study of Pain (IASP) defines pain as "an unpleasant sensory and emotional experience with actual or potential tissue damage described in terms of such damage". The objetive of this study was to analyze the efficacy and safety of the combination of metamizol - tramadol compared to metamizol - ketorolac in postoperative pain management in laparoscopic cholecystectomy Hospital Obrero No. 2. An analytical, longitudinal study, clinical trial randomized.The analysis was nonparametric data: ordinal and nominal variables with frequency tables; continuous and discrete variables with position measurements,Visual Analgesic Scale (EVA) hypothesis test U Mann-Whitney through the program SPSS® version 22.5 for Windows. The results showed that it is effective and safe use of the association scheme 1 (metamizol - tramadol) compared to scheme 2 (metamizol - ketorolac) EVA because the pain is significant (p <0.05) U test Mann-Whitney. In addition, both schemes have a satisfactory analgesic treatment compliance. However, they have similar adverse effects in both treatment regimens. Therefore the alternative hypothesis is accepted.

Keywords : Efficacy; safety; Tramadol; Metamizole; ketorolac; acute postoperative pain.

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