Abstract

DE ACHA TORREZ, Rafael; DOLZ TEJERINA, Helmut  and  DOLZ TEJERINA, Vladimir. Aquaporins, implications at pathologic models, of treatment and clinical role. Rev Cient Cienc Méd [online]. 2015, vol.18, n.2, pp.38-42. ISSN 2077-3323.

Aquaporins are a group of membrane integral proteins which structure and function start's from the simple concept of the transmembrane fluid movement, however the complexion of its utility it's beginning to rise in comprehension. It has been implicated in multiple pathogenic models from al sorts. From it's role in the widely studied transport and urine of normal concentration generation, its role on insipid diabetes pathogenesis and the hormonal response to vasopressin. Roles in the tumorigenesis of many cancers, and its role as a prognostic factor expression in cutaneous neoplasms. Also it's role in the pathogenesis and potential utility in the therapy of the central nervous system CNS lesions, as well as it is for the understanding of the development of new therapeutic techniques.

Keywords : Aquaporins; Molecular therapy; role.

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