versão impressa ISSN 1813-5363
BENITES VILCHEZ, Julio et al. Antioxidant, antibacterial and analgesic activities of Mangifera indica L. extracts. BIOFARBO [online]. 2010, vol.18, n.2, pp. 10-19. ISSN 1813-5363.
Several studies have shown that different parts of mango (roots, stems, bark, flowers and fruits) have different pharmacological properties, being used to treat menorrhagia, scabies, diarrhea, syphilis, amoebas and skin infections. The use of extracts of leaves and stem have been described in traditional medicine as an analgesic for the treatment of dental pain and muscular, inflammatory diseases and anemia. In this study we evaluated the antioxidant activities, through the fading test radical 2,2-Diphenyl-1-picryl-hidrazil (DPPH*), total phenolic content by Folin-Ciocalteu and antibacterial and analgesic activity on seven varieties of Mangifera indica L., bark. The results showed that ethanol extract showed better activity than water extract. However, free radical scavenging activity of control was greater than the free radical scavenging activity of different extracts. The CMI for measuring the antibacterial activity was determined by the equation of the line, we observed that the ethanol extracts of three varieties of crust Mangifera indica L., Pica, 3 Gloria and Kent, and showed an antibacterial effect against Escherichia coli, with respect Cefotaxime. Finally, we evaluated the analgesic activity of aqueous and ethanol bark extracts of Mangifera indica L. variety of Pica, using hot plate test in Sprague-Dawley rats after ip administration: physiological saline solution, diclofenac and morphine (positive controls) as references and aqueous and ethanol extracts at 100mg/kg and 200mg/kg dose weight. The results showed that the extracts have analgesic activity. Therefore M. indica bark has antioxidant and analgesic activity correlated with the presence of bark polyphenols in all evaluated.
Palavras-chave : antioxidant; antibacterial; analgesic activity; Mangifera indica L..