versão impressa ISSN 1813-5363
TRONCOSO VALENZUELA, Marjorie et al. Mangifera indica and Psidium guayava: determination of antimicrobial activity of lyophilized peels in the formulation of a hydroalcoholic lotion for acne. BIOFARBO [online]. 2010, vol.18, n.2, pp. 1-9. ISSN 1813-5363.
Mangifera indica and Psidium guayava has been significantly used in folk medicine of different countries around the world, ethno-medical use is well documented, have different pharmacological activities such as hypoglycemia, antimicrobial, antiviral, anti-inflammatory, antioxidant, antiallergic, hypotensive, hepatoprotective, antitussive and anti-diarrhea. The peels of these fruits are waste products and simultaneously generate a problems at the time of disposal taking into account all these bioactive compounds, such as flavonoids, tannins, ascorbic acid, polyphenols were formulated hydroalcoholic lotions of the liofilized of peel Mangifera indica and Psidium guayava to which were made stability studies, evaluating the change in pH, centrifugation, heat stress, organoleptic controls and microbiological control. We performed patch test to potencial assess the sensitivity reaction that can cause the lotions, checking that they do not cause skin irritation. Finally, the MIC was determined for measuring the antibacterial activity of the lotions about S. epidermidis and S. aureus, result indicate that lotions M. indica 0,1% and P. guayava 1% showed good activity against these strains, like clindamycin.
Palavras-chave : Mangifera indica; Psidium guayava; lotion; lyophilized; MIC.