versão impressa ISSN 1813-5363
Plantago major, also known as llantén, is a herbaceous plant that is found mainly in the template and warm regions of all Bolivia. The leaves of this plant are tradicionally used due to their medicine activity as an astringent, antiinflamatory, diuretic and antiulcerous factor. However, this last activity has not been cientifically validated throught biological tests in our country. In the current study, the activity of both ethanolic and aqueous extract from Plantago major was evaluated through the Induction Test of Gastric ulcer by absolute ethanol. The results were subjected to an statistical analysis, and thus, the SPSS statistical program was applied with a 95 % interval in order to offer reliable evidence about the test, so the aqueous extract as well as the ethanolic extract of Llantén was found to have 500 mg/ kg poid, a fact that is showing a gastric protective activity similar to omeprazol; the pattern medication. The components that are probably responsible for the gastroprotective activity were also determined: they are the tanines and the flavonoids
Palavras-chave : Activity Gastroprotective; Plantago major; gastric ulcer; tanines and flavonoids.