Abstract

ALANOCA, Gladys  and  ARCE, Mauricio. TORSADES DE POINTES DUE TO PROLONGED QT INTERVAL BY AMITRIPTILIN USE. Rev. Méd. La Paz [online]. 2021, vol.27, n.2, pp.42-48. ISSN 1726-8958.

The QT interval representas ventricular electrical activity, both depolarization and repolarization. We define a prolonged QT interval as a corrected QT measurement> 450 ms in men and> 470

Two major groups are distinguished within the long QT syndrome: congenital, associated with mutations in certain genes, and the acquired variant.

Long QT syndrome is a rare group of entities that are manifested on ECG by prolongation of the QT interval and predisposition to polymorphic ventricular tachycardia.

One of the main etiologies of acquired congenital QT syndrome is the use of QT- prolonging drugs. At present, the list of these is extensive and is constantly growing.

Prolongation of the QT interval can predispose to the development of severe polymorphic ventricular tachycardia called torsades de pointes (TdP), which is not a very common presentation but is a cause of sudden death.

In this report, we present a case of the development of severe polymorphic ventricular tachycardia due to the use of amitriptyline.

Keywords : Acquired long QT syndrome; torsades de pointes; amitriptylin.

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