Abstract

REAL DELOR, Raúl  and  FRIDMAN D'ALESSANDRO, Valeria. CLINICAL MANAGEMENT OF ADULTS WITH PROLONGED FEVER. Rev. Méd. La Paz [online]. 2016, vol.22, n.2, pp.18-28. ISSN 1726-8958.

Introduction: Prolonged febrile syndrome (PFS) is all hyperthermia that persists for at least 10 days without diagnosis, despite an initial etiologic study. Objective: To determine the most frequent causes of adult with PFS. Methodology: observational, descriptive, retrospective, cross-sectional study that included 57 patients admitted to the Medical Clinic Service and emergency rooms from the National Hospital (Itauguá, Paraguay) from January 2010 to November 2015. It was considered PFS to all patients with hyperthermia that persists at least 10 days without diagnosis, despite basic studies. Results: The PFS affect preferentially men, from the Central Department, with an average age 41 ± 17 years. The average duration off ever was 47 ± 38 days. The most frequent diagnosis clue was visceromegaly. The most frequent etiology were visceral leishmaniasis, acute lymphoblastic leukemia and bacterial endocarditis. En 17.5% we didn't reach the final diagnosis. The average time required for diagnosis was 4 days. The majority, 90%, were discharged alive, with or without diagnosis. There were 5 deaths, of which in 2 subjects the fever was considered as the cause of death. Conclusions: The most frequent causes of PFS were infections, especially visceral leishmaniasis, and leukemias.

Keywords : prolonged febrile syndrome; infections; malignancies; diagnostic clue; visceral leishmaniasis.

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