Abstract

AMARU, Ricardo et al. CELL THERAPY IN CHRONIC ULCERS TREATMENT. Rev. Méd. La Paz [online]. 2016, vol.22, n.1, pp.20-26. ISSN 1726-8958.

Introduction: Chronic pressure ulcers result from an ischemic necrosis of the skin and subcutaneous tissue. This type of ulcers occurs in patients physically restrained by different etiology and in advanced stages increase mortality. Cell therapy allows to regenerate the function of injured tissues by using somatic stem cells that differentiate and proliferate into mature cells on order to repair injured tissues. Objective: To demonstrate the effectiveness ofusing Somatic Stem Cells obtained from bone marrow in chronic pressure ulcers treatment, as a likely therapeutic option to unsuccessful conventional treatments. Method: It was studied 4 patients with chronic pressure ulcers in advanced stages and refractory to conventional treatment. It was obtained Somatic Stem Cells from the bone marrow and followed a process of seeding on a weekly basis. Results: Somatic Stem Cells seeded in chronic pressure ulcers differentiated into muscle, connective, epithelial and subcutaneous tissues. The repair of injured tissues lasted between 30 to 69 days. Conclusion: Cell therapy by using Somatic Stem Cells from bone marrow constitutes a therapeutic option in chronic ulcers of advanced stages and refractory to conventional treatment.

Keywords : Cell Therapy; Bolivia; Somatic Stem Cells.

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