Abstract

QUISBERT GUTIERREZ, Hans F.  and  LINARES MENGOA, Miriam. PRIMARY BILIARY CIRRHOSIS - AUTOIMMUNE HEPATITIS OVERLAP SYNDROME. CONTRIBUTION OF NEW CASE. Rev. Méd. La Paz [online]. 2011, vol.17, n.2, pp.29-33. ISSN 1726-8958.

The term"overlap sindrome" has been introduced to the field of hepatology to describe variant forms of autoimmune hepatitis (AIH) which present with characteristics of AIH and primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC). We present a case of an elderly female, without past medical history of alcohol, medication or hepatotoxic substances intake, with negative serology studies for viral hepatitis. Clinically with signs of chronic hepatophaty. The patient presents mixed clinical, serologic, immunologic and histologic features of Autoimmune Hepatitis and Primary Biliary Cirrhosis. We postulate this is a variant or overlap syndrome.

Keywords : Overlap; Autoimmune hepatitis; Primary biliary cirrhosis; Syndrome of Overlap.

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