Resumen

JAIMES CADENA, Marlon Orlando  y  BURGOS PORTILLO, Roxana Bernardet. LOS ANTAGONISTAS DE LOS RECEPTORES DE LA ANGIOTENSINA II A LA LUZ DE LOS ESTUDIOS DE MAYOR IMPACTO. Rev. Méd. La Paz [online]. 2009, vol.15, n.2, pp.58-66. ISSN 1726-8958.

Introduction: Angiotensin-receptor blockers constitute a recent group of medicaments for the treatment in hypertension, its usefulness has spread in addition to the managing of the cardiac Insufficiency, renal protection and acute myocardial infarction. Pharmacology: Alter renin-angiotensin-aldosterone system though of different form, blocking the unión of angiotensin II to its receptors (type 1) in numerous organs (muscle, adrenal gland and myocardium) and, its consequence, disable its vasopresor effect and aldosterone liberating. Conclusions: In hypertension. Angiotensin-receptor blockers are alternative to angiotensine-converting-enzime inhibitors when it is necessary to use these antihypertensives and the patient could not or should not use a medicament of the above mentioned subgroup. In renal protection. Though Angiotensin-receptor blockers have diminished the levels of proteinuria in renalpatients continued being an alternative to angiotensine-converting-enzime inhibitors. In cardiac insufficiency. Angiotensine-converting-enzime inhibitors are initial treatment, whereas Angiotensin-receptor blockers can be usefulin patients who do not tolerate them. In post-acute myocardial infarction. Angiotensine-converting-enzime inhibitors continued being treatment of choice and the alternative when patients do not tolerate these medicaments.

Palabras clave : Angiotensin-receptor blockers; Hypertension; Renal protection; cardiac Insufficiency Acute myocardial infarction.

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