Resumen

CACERES - SANCHEZ, L.; COCA-SALAZAR, A.  y  BOITRELLE, F.. Developmental origin of health and disease: relation between in utero exposure to atmospheric pollution and post-natal health. RevActaNova. [online]. 2018, vol.8, n.3, pp.290-306. ISSN 1683-0789.

Effects of atmospheric pollution on human health (e.g. respiratory, cardiac diseases) have been largely documented. During the last two decades, a growing body of evidences has reported an association between pre-natal exposure to atmospheric pollution and diseases, often idiopathic, later in life. The increasing number of idiopathic diseases in children indicates that atmospheric pollution affects fetus development during gestation. This study presents a bibliographic synthesis of the main studies that report evidences of the effects of atmospheric pollutants over fetus development, and inquire how pollutants can disturb in utero development and promote idiopathic case disease in children. In order to inquire the potential consequences due to prenatal pollutant exposure could impact Bolivian society, the critical values for contamination reported on the reviewed studies are contextualized in the Bolivian society using public data of particulate matter concentrations of 10 µm for the city of Cercado, Cochabamba of the Programa Nacional de Gestión de Calidad de Aire-Bolivia. This study shows the need of 1) studies of air quality and air pollution and their relationship with idiopathic diseases in bolivian society and 3) to understand the mechanisms by which atmospheric pollutants disrupt fetus development and the effects on post-natal health. In this way, prevention programs during gestation could be implemented in order to enhance post-natal health.

Palabras clave : Developmental Origen of Health and Disease (DOhAD); Idiopathic cases; Epigenetic; Air pollution; Bolivia.

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