Abstract

ALIAGA GUTIERREZ J, V et al. REPORT OF CASE OF CYCLOPIA, IN THE CITY OF EL ALTO 2022. Cuad. - Hosp. Clín. [online]. 2025, vol.66, n.1, pp.67-73.  Epub Sep 23, 2025. ISSN 1562-6776.

INTRODUCTION

Cyclopia is a congenital malformation, the product of a defect in the division of the forebrain that leads to alobar holoprosencephaly and the fusion of the eyes, affecting a central eye.

It is characterized by having a single orbit that contains the ocular structure. The prevalence of this malformation has been estimated at 1.05 per 100,000 births, including stillbirths, and is more common in females.

CLINICAL CASE

The objective of this document is to describe a clinical case of cyclopia that occurred at the Bolivian Japanese Model Municipal Hospital of the City of El Alto, in the 2022 administration. Pregnant patient who was admitted through the emergency service without having any prenatal control, resulting in the birth of a female newborn (with APGAR 7 at one minute and 0 at 10 minutes) with cyclopia (proboscis), weighing 2900 grams, who only survived 10 minutes.

DISCUSSION

The mechanisms of the pathogenesis of cyclopia are not clear, and the etiology of cyclopia is considered heterogeneous because environmental, teratogenic, chromosomal and monogenic agents have been related. Among other causes that have been related we can mention: intrauterine viral infections, diabetes, ingestion of ethanol and salicylates in the first trimester of pregnancy.

Keywords : cyclopia; holoprosencephaly; congenital malformations.

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