Aims:

Determine the frequency of ABO blood groups and Rh factor in the resident population of the La Paz and El Alto cities (altitude 3600 m.s.n.m.)

Methods:

It is a descriptive cross-sectional study. The study population was made up of people who attended the resident Clinical Epidemiology laboratory of the city in La Paz and El Alto, Bolivia, meeting selection criteria for the design. The sample calculation according to the design is 962. The population was people over 18 years of age and both sexes. Validated instruments were used for data collection, clinical history, as well as pre-analytical, analytical and post-analytical procedures in hematology. Blood groups and Rh factor were determined through the whole blood reaction for hemoclasification with monoclonal antisera reagents typing the ABO system (anti-A, anti-B) and anti-D for the Rh factor.

Results:

The most frequent blood group is group O, which corresponds to 73% N=704, group A represents 21% (N=205), group B with 4 % (N=40) and group AB gives a percentage of 1.35% (N=13). The Rh (+) factor was 97.61% and the Rh (-) factor was 2.39%, with a predominance of group “O” followed by group “A”.

Conclusion.

The results obtained in this research work demonstrate that the frequencies of the ABO and Rh blood system in the population of La Paz and El Alto continue to be predominantly group “O” with positive Rh factor in the vast majority, highlighting the studied sample of 962 people. The frequency in group “A” Rh(+) increases to 21.3%, group “B” to 4.16% and group “AB” 1.35%.