Abstract

PINILLA, Ramiro; APAZA, Helen  and  CLAROS, Nataniel. Microbiology of acute cholecystitis and antibiotic selection based on sensitivity profile. Cuad. - Hosp. Clín. [online]. 2023, vol.64, n.2, pp.36-43. ISSN 1562-6776.

Abstract AIM: To determine the microbiology and prevalence ofpositive bile culture un acute Cholecystitis. Research metodology: Consecutive case series nested in a cohort Results: 196 patients with a mean age of 46,5 años (DE± 14,735 años) were included, distributed by gender 88 female patients (44,9%) and 108 male patients (55,1 %). The mean leukocytosis was 10.000 x mm³ with 80% of neutrophils. The prevalence ofpositive bile culture in AC was in 64 patients (32,65%). The most cultivated germ was E. Coli in 28 patients (43,75 %). In the sensitivity of the antibiogram amoxilin with clavulanic acid shows 53,12% of resistence and when is used amoxicillin alone is 25,56%. Amikacin, ceftriaxon, cefepim, imipemen, chloranphenicol, ciprofloxacin, cotrimoxazole and gentamicin have sensitivity greater to 50%. In edematous AC the positive culture was 19,7%, hydrops gallblader 31,25%, in piocolecyst 50% and in retro gallbalder abscess was 79,16%. Conclusions: The prevalence positive bile culture was 32,65% with E. Coli as the most frequent germ. The choice of antibiotic should be based on the knowledge of the hospitals microbiology and the sensitivity determinated by cultures and antibiogram

Keywords : Acute Cholecystitis; microbiology.

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