Abstract

SUXO-TEJADA, Marlene I et al. Seroprevalence, SARS-COV-2 clinical characteristics and ABO system in 85 high-altitude resident volunteers. La Paz, Bolivia. Cuad. - Hosp. Clín. [online]. 2022, vol.63, n.2, pp.45-52. ISSN 1562-6776.

Abstract Objective: To determine the seroprevalence, clinical characteristics of SARS-COV-2 and its relationship with the ABO system in 85 high-altitude resident volunteers. Material and Methods: Observational, cross-sectional analytical study. Lateral flow tests with venous blood plasma, oxygen saturation, heart rate, respiratory rate were performed, and a survey on demographic and clinical characteristics was applied. Results: Information was obtained from 85 volunteers, 64.71% womenand35.29%men. Theagewas 37.42±14.7years. 15.3% hadpositive IgM and IgG, 58.8% negative, 21.2% negative IgM andpositive IgG, and 4.7% positive IgM and negative IgG. In the 4 groups, most were asymptomatic, with 15.38% being presymptomatic in positive IgM IgG and symptomatic in similar proportions in the 4 groups. 27% declared some comorbidity, 8% of the positive IgM and IgG group with obesity; 39% of the IgM-IgG+ group with obesity and one pregnant; 50% of the IgM+ IgG- group with asthma and lumbago and 26% of the IgM and IgG negative group with 2 pregnancies, 2 gastritis and 1 erythrocytosis. In relation to blood type, the most frequent was 0 positive with 92.8%, followed by A positive with 4.8%, A negative with 1.2% and B positive also 1.2% (p>0.05). Conclusions: The clinical characteristics of COVID-19 and the seroprevalence of IgM and IgG in inhabitants of high altitudes are similar to those in the plains

Keywords : high altitude; COVID-19; clinical symptoms; seroprevalence.

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