Abstract

NIETO-CORONEL, MT; FERAUDY-FOURNIER, C  and  REYES-GONZALES, A. Multicenter giant cell tumor (osteoclastoma), incidental diagnosis of parathyroid adenoma Case Report. Cuad. - Hosp. Clín. [online]. 2020, vol.61, n.1, pp.73-84. ISSN 1562-6776.

Giant Cell Tumors (TDG), also called Osteoclastomas or Brown Tumors when they are within the endocrinological sphere, are one of the least frequent, most controversial and least predictable tumors in their behavior. They occur as a consequence of excess osteoclastic activity, as occurs in the case of Hyperparathyroidism, which is a common endocrine disorder, generally asymptomatic and diagnosed by the fortuitous finding of hypercalcemia. Diagnosing osteoclastomas is usually challenging, the high index of suspicion is essential, and biopsy is the gold standard for diagnosis. We present the case of a 42-year-old man who presented pathological fractures of the right radius and left tibia, a bone sean with Tc-99m with múltiple bone lesions, elevated parathyroid hormone (PTH), hypercalcemia, parathyroid sean with MIBI with the presence of parathyroid adenoma. , the biopsy of the bone lesions with the presence of multinucleated giant cells corresponding to osteoclastomas; Parathyroidectomy was performed and histopathological examination confirmed the presence of a parathyroid adenoma.

Keywords : parathyroid adenoma; osteoclastoma; hyperparathyroidism; brown tumor.

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