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Cuadernos Hospital de Clínicas

Print version ISSN 1562-6776

Abstract

VIRUEZ-SOTO, J A et al. Lactate clearance at high altitude. Cuad. - Hosp. Clín. [online]. 2019, vol.60, n.1, pp.32-36. ISSN 1562-6776.

Abstract Objective: To characterize the lactate clearance on criticaiiy ill patients, at high aititude. Desing: Prospective cohort study. Field: Critical Care Unit of "Hospital del Norte" in El Alto, La Paz (Bolivia), during the period April 25, 2016-June 01, 2018. Participants: Críticaiiy ill patients residents of high aititude at Ieast the Iast 6 months, admitted to the Adult Critical Care Unit. Results: 250 patients were included, with survival of 68%, age average of 50 years; in the 170 survivors, lactate clearance average was 26%, in contrast with 80 deceased patients who presented an increased lactate level of 25%, p ≤ 0.05, both of them through ANOVA test. In high landers críticaiiy ill patients, relative risk of lactate clearance > 26% and survival was 2.7 with sensitivity 0.72 and specificity 1. Discussion and Conclusions: Lactate clearance in críticaiiy ill high landers dwellers, is associated with survival and it should be considered also as a reanimation objective, comparable to other studies developed in different latitudes.

Keywords : Lactate; clearance; high aititude; critical care.

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