Abstract

HAYES DORADO, Juan Pablo. Short stature: Treatment with recombinant human growth hormone. Rev. bol. ped. [online]. 2016, vol.55, n.1, pp.23-28. ISSN 1024-0675.

Short stature may cause concern for children and their parents; on the other hand, represent the first sign of an underlying disease. It is important to make a detailed assessment of children with short stature to identify its etiology. Treatment of short stature is aimed at the primary etiology; therapy with recombinant human growth hormone (rhGH) is indicated in certain patients. Eight indications of rhGH in children with short stature have been approved: Growth hormone deficiency, chronic kidney disease, Turner syndrome, Prader Willi syndrome, small for gestational age with failure to catch up to the normal height percentiles, idiopathic short stature, SHOX gene haploinsufficiency and Noonan syndrome. Early identification and appropriate treatment of short stature is associated with better outcomes for patients.

Keywords : Short stature; recombinant human growth hormone; growth hormone deficiency.

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