Abstract

SIACAR BACARREZA, Sandra; APARICIO RODRIGUEZ, Amparo  and  SOLIZ ALDANA, Olga. Neonatal Screening: detection congenital hypothyroidism. Hospital Materno Infantil of Caja Nacional de Salud. Rev. bol. ped. [online]. 2014, vol.53, n.3, pp.121-124. ISSN 1024-0675.

Introduction: congenital hypothyroidism is one of the most common endocrinopathies in children with irreversible consequences when early diagnosis and treatment isn t performed. Objective: detection of congenital hypothyroidism through newborn screening in the Hospital Materno Infantil of the CNS. Methods: quantification of TSH in newborns (8957) was performed by the method of immunofluorescence to time delayed (DELFIA), since June 2012 to December 2013. TSH levels greater than 10 mIU/ml is considered suspicious, and full thyroid profile in venous blood is requested for confirmation. For etiologic diagnosis thyroid scintigraphy was performed without delay treatment. Results: screen coverage was 80.3%. Primary congenital hypothyroidism in 3 children was confirmed. Scintigraphy in 2 described sublingual thyroid. Treatment was initiated before the third week of life. Conclusions: 1:2985 incidence was found, similarly as described in the international literature. The most common cause is thyroid dysgenesis. The coverage achieved is still below world standards.

Keywords : Neonatal screening; hypothyroidism; thyroid dysgenesis.

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