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Revista de la Sociedad Boliviana de Pediatría

On-line version ISSN 1024-0675


PAGANINI, Hugo  and  SANTOLAYA DE P., María Elena. Diagnosis and treatment of febrile neutropenia in pediatric cancer patients Consensus of the Sociedad Latinoamericana de Infectología Pediátrica. Rev. bol. ped. [online]. 2011, vol.50, n.2, pp.79-111. ISSN 1024-0675.

This document is a consensus guideline on the "Diagnosis and treatment of febrile neutropenia in children with cancer" developed by the Committee for Infectious Diseases in Immunocompromised Children of the Sociedad Latinoamericana de Infectología Pediátrica. This guideline discusses the management of febrile neutropenia focused on Latin American children with cancer. It is based on a thorough review of the literature, with particular attention to experiences reported by centers within the continent in order to provide recommendations applicable to the region. The manuscript includes a description of the regional epidemiology of cancer and infections in children, recommendations for clinical and laboratory studies required for patient management, description of a classification method to identify patients at different risk for invasive bacterial infections, outpatient and inpatient general care strategies and differential treatment strategies adjusted to local epidemiological realities, different algorithms for patient follow-up according to clinical course, a discussion of the rationale for prophylaxis strategies in specific situations including general guidelines for antifungal treatment. The Guidelines intend to provide practical, evidence-based recommendations in order to promote the best possible management for children with cancer, fever and neutropenia, throughout oncology centers of Latin America.

Keywords : febrile neotropenia; cancer.

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