Abstract

RIOS VALDEZ, Claudia Verónica; NAVIA BUENO, Maria del Pilar; DIAZ VILLEGAS, Manuel  and  SALAZAR FUENTES, H. Jorge. Risk factors associated to neonatal sepsis. Rev. bol. ped. [online]. 2005, vol.44, n.2, pp.87-92. ISSN 1024-0675.

Objectives: Identifying risk factors and to what degree are these associated to early and delayed neo natal sepsis. Method: An analytical study was carried out observing cases and their follow-up at the Neonatology Department of the Women's Hospital in La Paz, Bolivia. The study included 322 newborn clinical histories, 108 cases and 214 follow-ups. Results: 322 clinical histories were revised. Risk factors that were significant for neo natal sepsis, either early of delayed were: premature birth (OR 5.47, IC 95% 2.14-14.83), low birth weight (OR 3.09, IC 95% 1.55-6.16), premature membrane rupture (OR3.87, IC 95% 2.06-7.32), urinary tract infection (OR 3.21, IC 95% 1.49-6.89) and "chorioarnnionitis" (OR 4.69, IC 95% 1.05,-21.63). Significant risk factors for delayed neonatal sepsis were invasive procedures such as high blood pressure (OR 114.44, IC 95% 37.90-366), use of main pathway (OR 5.41, IC 95% 2.57-11.4) and mechanical ventilation (OR 3.26, IC 95% 1.6-6.66). Risk factors for newborn deaths were: premature births, (OR 3.3, IC 95% 1.6-6.87), low birth weight (OR 13.07, IC 95% 6.84-25.13), urinary tract infection in the mother (OR 2.08, IC 95% 1.03-4.15) use of main pathway (OR 8.46, IC 95% 4.43-16.26) and mechanical ventilation (OR 17.94, IC 95% 9.17-35.45) Conclusions: findings in this study show that sepsis causes neonatal death be it early or delayed and that it is caused by several factors which may originate either in the mother or the baby which turn into risk factors that may be treated or prevented once they are diagnosed.

Keywords : risk factors; early neonatal sepsis; delayed neonatal sepsis; neonatal mortality.

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