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Gaceta Médica Boliviana

Print version ISSN 1012-2966On-line version ISSN 2227-3662

Abstract

CONDORI FLORES, Liz Nela  and  MAMANI GARABITO, Jhanneth. CA 15-3 and CEA markers in the breast. Gac Med Bol [online]. 2025, vol.48, n.2, pp.102-106.  Epub Dec 31, 2025. ISSN 1012-2966.  https://doi.org/10.47993/gmb.v48i2.1000.

Breast cancer is a leading cause of morbidity and mortality in women worldwide. Its occurrence is linked to demographic, reproductive, and lifestyle factors, making it essential to strengthen early detection and clinical follow-up strategies. The tumor markers CA 15-3 and CEA are used to assess tumor activity and support disease management.

Objective:

to determine the tumor markers CA 15-3 and CEA in breast cancer patients at the National Cancer Institute of Cochabamba, Bolivia. Methods: This was a quantitative, descriptive, and correlational study with a non-experimental, cross-sectional design. The study included 89 patients diagnosed with breast cancer who attended the National Cancer Institute.

Results:

27.0% of patients tested positive for the CEA marker, and 20.2% tested positive for CA 15-3. Regarding sex, 25.8% of women tested positive for CEA and only 1.1% of men. For CA 15-3, 19.2% of women showed elevated levels and 1.0% of men; no significant correlation was found between sex and tumor markers. The 41-50 age group was more frequently affected, reflecting tumor activity rather than age.

Conclusion:

The CA 15-3 and CEA markers are useful in the clinical follow-up of breast cancer patients; however, no statistically significant correlation was found with the variables evaluated.

Keywords : carcinoembryonic antigen; breast neoplasms; biological tumor markers.

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