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Gaceta Médica Boliviana
Print version ISSN 1012-2966On-line version ISSN 2227-3662
Abstract
ESPINOZA ANTEZANA, Magaly et al. Evolution of antibiotic resistance of microorganisms isolated from infected diabetic foot. Gac Med Bol [online]. 2024, vol.47, n.1, pp.67-71. Epub June 01, 2024. ISSN 1012-2966. https://doi.org/10.47993/gmb.v47i1.798.
Objectives:
to evaluate the evolution of antibiotic resistance of microorganisms isolated from infected diabetic foot in patients treated at the Viedma Clinical Hospital, in the 2014, 2016, 2018 and 2021 administrations
Methods:
observational, descriptive, retrospective, cross-sectional research with a quantitative approach, 268 cultures and antibiograms of patients with a diagnosis of diabetic foot infection were the sample analyzec with a 2,82 % maximum admitted error.
Results:
312 microorganisms were identified, with 71,5% Gram- negative bacteria were the most frequent, of these Klebsiella spp with 17,9 % and Escherichia coli with 17,6% predominated, whose resistance to ciprofloxacin, sulfa trimethoprim and gentamicin increased, the most isolated non-fermenting Gram negative bacilli were Pseudomonas spp and Acinetobacter spp whose resistance to cephalosporins, ciprofloxacin and carbapenems increased. On the other hand, with 16,3 % Staphylococcus aureus was the most identified Gram-positive bacteria, methicillin resistance from 17 % in 2014 increased to 25 % in 2021.
Conclusions:
enterobacteriaceae were the most frequently isolated microorganisms, whose resistance was associated with the production of extended spectrum beta-lactamases (ESBL).
Keywords : antibiotics; enterobacteriaceae; infection; diabetic foot; resistance.