Introduction:

Obesity is a pathological state characterized by an excessive accumulation of adipose tissue, which secretes adipokines where there is Leptin, that is involved in important metabolic functions such as appetite control and body weight.

Objectives:

a study was carried out on the correlation between the serum Leptin concentration with anthropometric indicators and biochemical parameters in patients between 5 and 15 years old, overweight and obesity.

Methods:

the cross-sectional descriptive observational study was carried out, with 148 patients between 5 and 15 years of age, biochemical tests were performed to evaluate the concentration of Leptin Glucose, insulin, lipid profile and anthropometric indicators BMI, % BF y WHR.

Results:

positive correlations were found between serum Leptin concentrations with BMI (75.4; p <0.000), the (% BF) Body fat percentage (70.7: p <0.000) and the (WHR) Waist Ratio height (75,4 p <0.000). A low correlation was observed between the Leptin concentration and Total Cholesterol, with the concentration of HDL Cholesterol an inverse correlation was found in male sex, while Triglycerides presented higher levels in the adolescent group, there was no statistically significant. Also, we did not find a significant between the determination of Leptin and glycemia, on the contrary, insulin presented a statistically significant higher correlation (p <0.000).

Conclusion:

this study shows the existence of a statistically significant correlation between serum Leptin with anthropometric indicators and biochemical parameters in patients between 5 and 15 years of age, who are overweight or obese.

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