Abstract

THERAN LEON, Juan Sebastian; VILLALOBOS, Mayra Alejandra; ESTEBAN BADILLO, Laura Yibeth  and  DULCEY, Luis Andres. Systemic Sclerosis and Lupus Overlap Syndrome. Gac Med Bol [online]. 2021, vol.44, n.2, pp.265-267. ISSN 1012-2966.  https://doi.org/10.47993/gmb.v44i2.314.

Autoimmune pathologies are conditions caused by an abnormal response of the immune system. Systemic sclerosis is an autoimmune disorder that affects the microvasculature of the gastrointestinal tract, lungs, kidneys, heart, skin and joints, with consequent fibrosis of the affected organs, while systemic lupus erythematosus is characterized by an aberrant activity of the immune system considered as a prototype of immune complex-mediated disease, leading to variable clinical symptoms; the overlap of two pathologies of the immune system is unusual, without mentioning the mixed connective tissue disease, and it is of great importance to identify a combined pathology since it has a great impact on the clinical characteristics, diagnosis, treatment and prognosis of the patient.

Keywords : systemic lupus erythematosus; overlap syndrome; systemic sclerosis.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )