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Gaceta Médica Boliviana

On-line version ISSN 1012-2966


ARANDIA-GUZMAN, Jaime  and  ANTEZANA-LLAVETA, Gabriela. SARS-CoV-2: structure, replication and physiopathological mechanisms related to COVID -19 . Gac Med Bol [online]. 2020, vol.43, n.2, pp.170-178. ISSN 1012-2966.

SARS-CoV2, which causes severe acute respiratory syndrome, also called COVID-19, was reported in late 2019 as a new betacoronavirus in exposed persons in a seafood market in Wuhan, China. The virus has since spread rapidly, causing a pandemic, affecting several countries to a greater or lesser extent. Currently, there is a variety of information disseminated about the virus and the disease; knowledge about the physiopathology and how it should be managed has changed over time. Despite the interest that has been generated in the physiopathological mechanisms of the disease and its complications, these have not been completely deciphered. The present article makes a systematized review of the structure, replication and physiopathological aspects related to SARS-CoV2, which has caused a high rate of morbimortality in the population worldwide.

Keywords : SARS-CoV-2; COVID-19; betacoronavirus; mechanisms; morbidity.

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