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Gaceta Médica Boliviana

On-line version ISSN 1012-2966


ALEGRE ANDRADE, Patricia. Dexmedetomidine in spinal anesthesia with cesarean . Gac Med Bol [online]. 2020, vol.43, n.2, pp.162-169. ISSN 1012-2966.

Dexmedetomidine an α-agonist, widely used and popular worldwide, with little knowledge about its use intrathecally in the Bolivian population, especially in obstetric patients. Objectives: evaluate the effect of spinal dexmedetomidine in obstetric anesthesia and observe the side effects of the medication. Methods: randomized and simple blind clinical trial. The sample consisted of 123 patients, each group of 41 patients meeting both criteria. Group B (bupivacaine + fentanyl); group D2 (bupivacaine + fentanyl + 2 µg dexmedetomidine) and group B3 (bupivacaine + fentanyl + 3 µg dexmedetomidine). Statistical analysis: it was carried out in SPSS® 25 and Microsoft Excel® 2016. With a confidence level of 95% and sampling error of 13%. Results: duration of the motor block was 106,5 ± 16 minutes in group B; 142,3 ± 28,2 minutes in group D2 and 145,6 ± 16,7 minutes in group D3. Being significant among the study groups (p value <0,000). MAP with statistical significance before and after birth. Significant heart rate at 15, 30 and 45 minutes (p value <0,000; 0,001; 0,004; 0.000 and 0,002). Ethylephrine in group B was 3,44 ± 1,8 ml; for group D3 it was 1,8 ± 2,7 ml and group D2 was 0,85 ± 1,6 ml. Conclusions: better hemodynamic stability with 2 µg dexmedetomidine, lower incidence of hypotension, use of vasopressors, limited complications and an excellent state of maternal sedation.

Keywords : Dexmedetomidine; caesarean section; spinal anesthesia.

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