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Gaceta Médica Boliviana

On-line version ISSN 1012-2966

Abstract

NINA GARCIA, Nelson M.  and  CUSSI CORONEL, Guiselle Alejandra.   Use of convalescent Plasma in COVID-19 patients . Gac Med Bol [online]. 2020, vol.43, n.1, pp.80-85. ISSN 1012-2966.

Coronavirus 2019 disease (COVID-19) represents one of the largest pandemics the world is facing and is producing a global health crisis. To date, there are no approved therapies or vaccines for this disease. Various therapeutic options are being explored and vaccines are being developed. Convalescent plasma is an interesting therapeutic option against COVID-19, as it has been successfully used in other viral outbreaks in the past. This therapy consists of collecting plasma from individuals recovered from the viral disease who developed antibodies. It is considered the only short-term strategy to confer immediate immunity to susceptible individuals. This review addresses the possible mechanisms of action of convalescent plasma, we give a panoramic view of the first studies carried out on COVID-19, as well as the necessary procedures to implement this therapy.

Keywords : COVID-19; SARS-CoV-2; convalescent plasma.

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