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Gaceta Médica Boliviana

On-line version ISSN 1012-2966


LIMACHI-CHOQUE, Jhonny Wilson; ROJAS-CABRERA, Ernesto; VERDUGUEZ-ORELLANA, Aleida  and  EID-RODRIGUEZ, Daniel. Is the intralesional treatment of cutaneous Leishmaniasis safe against the risk of mucosal complications? . Gac Med Bol [online]. 2020, vol.43, n.1, pp.18-22. ISSN 1012-2966.

Objective: to assess the long-term safety against the risk of mucosal complications of intralesional pentavalent antimonials (PA) in patients with cutaneous Leishmaniasis compared to the systemic use of PA. Methods: retrospective longitudinal quantitative observational study. A total of 66 clinical records of patients diagnosed with cutaneous Leishmaniasis in Isiboro Secure Park were analyzed between 2012 and 2016. A total of 46 systemic and 20 intralesional treatments were evaluated. Results: clinical evaluation 4-7 years after healing of Leishmaniasis skin lesions showed no development of mucosal lesions. Likewise, no therapeutic failures, relapses or short-term adverse effects were reported. Conclusions: intralesional treatment was safe and effective in the long term and is a reliable option for the treatment of cutaneous Leishmaniasis avoiding the future complications of the disease.

Keywords : mucosal Leishmaniasis; intralesional treatment; systemic treatment; treatment safety.

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