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Gaceta Médica Boliviana
On-line version ISSN 1012-2966
Abstract
ZURITA CESPEDES, Brian Iván; CORTEZ CHAVEZ, Mauricio Ramiro; SALINAS CORTEZ, Pablo Rafael and SANTA CRUZ RODRIGUEZ, Concepción. Relationship between rotavirus and convulsive syndrome febrile and afebril. Gac Med Bol [online]. 2016, vol.39, n.2, pp.111-115. ISSN 1012-2966.
The Rotavirus is common cause of severe diarrhea in young children worldwide. Clinical manifestations include: liquid diarrhea, fever, and vomiting, leading to states of dehydration and typical gastroenteritis; In addition, they may present multiple neurological complications, such as febrile seizures or afebrile seizures. The actual prevalence of these seizures would range between 2 and 6%. Their pathophysiology is still uncertain, but theories have been proposed that try to explain a possible mechanism, including genetic factors, racial, serotype distribution, pro-convulsive factors and even alterations of the blood-brain barrier. Although this is a syndrome whose etiology is not unique, rotavirus infection will be taken into account since it has been identified more frequently, especially in afebrile patients, thus avoiding unnecessary procedures and interventions for its diagnosis.
Keywords : rotavirus; febrile seizure; afebrile seizure; genetic predisposition to disease; nitric oxide; benign childhood seizures.