Abstract

RAMIREZ, Dionicel et al. Associations between nephrolithiasis, citrate and other metabolites in uriñe and serum of patients. Gac Med Bol [online]. 2015, vol.38, n.2, pp.6-10. ISSN 1012-2966.

Objective: to determine theassociations between nephrolithiasis,citrateandothers metabolites presentinurineand serum of patients with the objective of adapting the diagnosis in care protocols nephrolithiasis. Materials and Methods: descriptive, transversal investigation that included subjects with nephrolithiasis without thiazide therapy, thesample wascomposed of 100 patients who metabolicevaluation was performed in 24-hour uriñe and blood serum samples. The dates were applied descriptive statistics and frequency dispersión and it's compared the frequency of variables with Chi-square. Results:93% of patients with lithiasis had hypocitraturia.The hypernatresiuria occurred in 71.0%, 59.1% had hyperchloremia, the most frequent associations were the hypernatruremia hyperchloremia (50.5%) and hyperuricosuria + hypernatruria (30.1%). Conclusions: exist a high prevalence of hypocitraturia in patients with nephrolithiasis; the condition can occur alone or associated with uriñe biochemical abnormalities blood serum; hyperchloremia more hypermagnesemia is the only dúo blood factors that characterize the patient with nephrolithiasis and hypocitraturia; and often a combination of alteration uriñe parameter and blood serum in patients with nephrolithiasis.

Keywords : citrate; nephrolithiasis; mineral metabolism; 24 hours uriñe; serum.

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